Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 13/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 13/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755384 | 0.89 | PDGFRB (0.50) | NQO2ALDH1A1KDM4ESMN1; SMN2PDGFRB | |
| SCHEMBL9755391 | 0.84 | CYP1A1 (0.53) | NQO2ALDH1A1KDM4ESMN1; SMN2PDGFRB | |
| SCHEMBL14983509 | 0.82 | PDGFRB (0.58) | NQO2PDGFRBPDGFRA | |
| SCHEMBL12068383 | 0.82 | KDM4E (0.50) | NQO2ALDH1A1KDM4ESMN1; SMN2PDGFRB | |
| SCHEMBL27765191 | 0.80 | ALDH1A1 (0.60) | NQO2ALDH1A1KDM4ESMN1; SMN2PDGFRB | |
| SCHEMBL2138144 | 0.80 | ALDH1A1 (0.60) | NQO2ALDH1A1KDM4ESMN1; SMN2PDGFRB | |
| SCHEMBL12068382 | 0.78 | NQO2 (0.44) | NQO2PDGFRBPDGFRA | |
| SCHEMBL8317211 | 0.78 | NQO2 (0.48) | NQO2ALDH1A1KDM4ESMN1; SMN2PDGFRB | |
| SCHEMBL8318079 | 0.78 | NQO2 (0.44) | NQO2ALDH1A1KDM4ESMN1; SMN2PDGFRB | |
| SCHEMBL3968488 | 0.77 | ALDH1A1 (0.53) | NQO2ALDH1A1KDM4ESMN1; SMN2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | disclosed |