Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 15/20 | 0.66 |
| ▸ | HTR1B | P28222 | 11/20 | 0.66 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887467 | 0.85 | HTR1D (0.69) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL8886099 | 0.82 | HTR1D (0.69) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL8315482 | 0.80 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8316283 | 0.80 | HTR1D (1.00) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL7435894 | 0.75 | HTR1D (0.60) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL8315256 | 0.74 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL3201298 | 0.73 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8314164 | 0.73 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8316440 | 0.73 | HTR1D (1.00) | HTR1DHTR1BDRD2 | |
| SCHEMBL7442744 | 0.72 | HTR1D (0.81) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011435-A2 | NEW CENTRALLY ACTING 6,7,8,9-TETRAHYDRO-3H-BENZ(e)INDOLE HETEROCYCLICS | THE UPJOHN COMPANY (US) | 1991-08-08 | — | — | WO | disclosed |