SCHEMBL9755601

SCHEMBL9755601

CCCCc1nc(Cl)c(CO)n1Cc1ccc(OCc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 4/20 0.68
AGTR2 P50052 4/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159 0.91 AGTR1 (0.81) AGTR1AGTR2
SCHEMBL520 0.90 AGTR1 (0.68) AGTR1AGTR2
SCHEMBL10532577 0.86 AGTR1 (0.68) AGTR1AGTR2
SCHEMBL267 0.83 AGTR1 (0.76) AGTR1AGTR2
SCHEMBL227 0.82 AGTR1 (0.73) AGTR1AGTR2
SCHEMBL9755600 0.82 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL8793373 0.81 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL251 0.81 AGTR1 (1.00) AGTR1AGTR2
SCHEMBL9039844 0.80 AGTR1 (0.53) AGTR1AGTR2
SCHEMBL395 0.80 AGTR1 (1.00) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991012002-A1 IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT MERCK & CO., INC. (US) 1991-08-22 WO disclosed