Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043241 | 0.87 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9045655 | 0.86 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9039836 | 0.85 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9040463 | 0.84 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9041257 | 0.83 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9041914 | 0.82 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9755601 | 0.80 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL9045647 | 0.80 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9039392 | 0.78 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9755563 | 0.77 | AGTR1 (0.52) | AGTR1AGTR2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515535-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1996-01-17 | — | — | EP | disclosed |