Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755836 | 0.84 | GRIK1 (0.43) | GRIK1GRIK2CPA1MMESLC1A2 | |
| SCHEMBL1415114 | 0.76 | GRIK1 (0.48) | GRIK1GRIK2CPA1CYP2C19 | |
| Water SCHEMBL28049315 | 0.75 | GRIK1 (0.52) | GRIK1GRIK2CPA1CYP2C19 | |
| SCHEMBL24215021 | 0.74 | GRIK1 (0.55) | GRIK1GRIK2CPA1CYP2C19 | |
| SCHEMBL56402 | 0.74 | GRIK1 (0.55) | GRIK1GRIK2CPA1CYP2C19 | |
| SCHEMBL7114024 | 0.74 | GRIK1 (0.55) | GRIK1GRIK2CPA1CYP2C19 | |
| SCHEMBL7002066 | 0.74 | SLC1A2 (0.55) | GRIK1GRIK2CPA1SLC1A2CYP2C19 | |
| SCHEMBL891727 | 0.73 | GRIK1 (0.64) | GRIK1GRIK2CPA1CYP2C19 | |
| SCHEMBL5677958 | 0.73 | GRIK1 (0.46) | GRIK1GRIK2CPA1SLC1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL531801 | 0.72 | GRIK1 (0.53) | GRIK1GRIK2CPA1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |