Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 8/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5677958 | 0.91 | GRIK1 (0.46) | SLC1A2GRIK1GRIK2CPA1ALDH1A1 | |
| SCHEMBL12212883 | 0.81 | SLC1A2 (0.69) | SLC1A2GRIK1GRIK2ALDH1A1MEN1 | |
| SCHEMBL9755836 | 0.80 | GRIK1 (0.43) | SLC1A2GRIK1GRIK2CPA1TBXAS1 | |
| SCHEMBL891727 | 0.76 | GRIK1 (0.64) | GRIK1GRIK2CPA1TBXAS1CYP2C19 | |
| SCHEMBL8031351 | 0.75 | GRIK1 (0.53) | GRIK1GRIK2CPA1TBXAS1MEN1 | |
| SCHEMBL2137236 | 0.75 | GRIK1 (0.53) | GRIK1GRIK2CPA1ALDH1A1TBXAS1 | |
| SCHEMBL27930116 | 0.75 | SLC1A2 (0.62) | SLC1A2GRIK1GRIK2MEN1KMT2A | |
| SCHEMBL2147491 | 0.75 | SLC1A2 (0.62) | SLC1A2GRIK1GRIK2MEN1KMT2A | |
| SCHEMBL9755833 | 0.74 | GRIK1 (0.44) | SLC1A2GRIK1GRIK2CPA1CYP2C19 | |
| SCHEMBL6050002 | 0.74 | GRIK1 (0.75) | SLC1A2GRIK1GRIK2CPA1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171876-A1 | Processes for the production of alpha-difluoromethyl ornithine (DFMO) | BRISTOL-MYERS SQUIBB COMPANY | 2004-09-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171876-A1 | Processes for the production of alpha-difluoromethyl ornithine (DFMO) | ODC1, OTC, OAT | SLC1A2 2265/4885GRIK1 3335/4885GRIK2 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.