Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755833 | 0.84 | GRIK1 (0.44) | GRIK1GRIK2CPA1SLC1A2CYP2C19 | |
| SCHEMBL7002066 | 0.80 | SLC1A2 (0.55) | GRIK1GRIK2CPA1SLC1A2TBXAS1 | |
| SCHEMBL5677958 | 0.79 | GRIK1 (0.46) | GRIK1GRIK2CPA1SLC1A2FOLH1 | |
| SCHEMBL463194 | 0.77 | FOLH1 (0.56) | GRIK1GRIK2CPA1FOLH1GRM3 | |
| SCHEMBL8805759 | 0.76 | FOLH1 (0.54) | GRIK1GRIK2CPA1FOLH1GRM3 | |
| SCHEMBL9376537 | 0.74 | GRIK1 (0.53) | GRIK1GRIK2CPA1FOLH1TBXAS1 | |
| SCHEMBL891727 | 0.72 | GRIK1 (0.64) | GRIK1GRIK2CPA1FOLH1TBXAS1 | |
| SCHEMBL8031351 | 0.71 | GRIK1 (0.53) | GRIK1GRIK2CPA1FOLH1TBXAS1 | |
| SCHEMBL2137236 | 0.71 | GRIK1 (0.53) | GRIK1GRIK2CPA1FOLH1TBXAS1 | |
| SCHEMBL923062 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |