Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | ARG1 | P05089 | 4/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 3/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592278 | 1.00 | GRM8 (0.48) | GRM8GRM4ARG1GSRNAPRT | |
| SCHEMBL9755844 | 0.84 | POLB (0.51) | GSRKIF11NOS1POLBKMT2A | |
| SCHEMBL10591572 | 0.84 | POLB (0.51) | GSRKIF11NOS1POLBKMT2A | |
| SCHEMBL717650 | 0.81 | GRM8 (0.49) | GRM8GRM4NOS1CYP2C19PLOD2 | |
| SCHEMBL9726131 | 0.81 | GRM8 (0.46) | GRM8GRM4ARG1GSRNAPRT | |
| Lysine SCHEMBL30844060 | 0.80 | GSR (0.61) | GRM8GRM4ARG1GSRNAPRT | |
| SCHEMBL2239991 | 0.78 | CYP1A2 (0.58) | GRM8GRM4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2239985 | 0.78 | CYP1A2 (0.58) | GRM8GRM4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2352046 | 0.78 | GRIK1 (0.54) | GRM8GRM4ARG1GSRKIF11 | |
| SCHEMBL2352037 | 0.78 | GRIK1 (0.54) | GRM8GRM4ARG1GSRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019743-A2 | COMBINED TREATMENT WITH GnRH ANTAGONIST AND GnRH TO CONTROL GONADOTROPIN LEVELS IN MAMMALS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1991-12-26 | — | — | WO | disclosed |
| EP-0345990-A2 | Polypeptide compounds | ZENECA LIMITED (GB) | 1989-12-13 | — | — | EP | disclosed |