Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 6/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591572 | 1.00 | POLB (0.51) | POLBKMT2ATDP1KIF11GRM2 | |
| SCHEMBL10782936 | 0.92 | KIF11 (0.53) | POLBKMT2ATDP1KIF11GRM2 | |
| SCHEMBL11694404 | 0.86 | GRM2 (0.41) | POLBKMT2ATDP1KIF11GRM2 | |
| SCHEMBL9630987 | 0.85 | GSR (0.47) | POLBKMT2ATDP1ALPIPKM | |
| SCHEMBL9755838 | 0.84 | GRM8 (0.48) | POLBKMT2ATDP1KIF11GSR | |
| SCHEMBL10592278 | 0.84 | GRM8 (0.48) | POLBKMT2ATDP1KIF11GSR | |
| SCHEMBL6823559 | 0.84 | CES2 (0.47) | POLBKIF11MDM2 | |
| SCHEMBL9631019 | 0.84 | GSR (0.55) | POLBKMT2ATDP1GSRLTA4H | |
| SCHEMBL28258416 | 0.84 | MDM2 (0.42) | POLBKMT2ATDP1KIF11GRM2 | |
| SCHEMBL28992842 | 0.84 | GSR (0.55) | POLBKMT2ATDP1GSRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019743-A2 | COMBINED TREATMENT WITH GnRH ANTAGONIST AND GnRH TO CONTROL GONADOTROPIN LEVELS IN MAMMALS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1991-12-26 | — | — | WO | disclosed |
| EP-0345990-A2 | Polypeptide compounds | ZENECA LIMITED (GB) | 1989-12-13 | — | — | EP | disclosed |