Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27951597 | 0.84 | TBXAS1 (0.50) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL9763970 | 0.83 | LMNA (0.56) | ALDH1A1F7F3SARM1SIRT2 | |
| SCHEMBL10591572 | 0.82 | POLB (0.51) | NOS1 | |
| SCHEMBL9755844 | 0.82 | POLB (0.51) | NOS1 | |
| Lysine SCHEMBL7592433 | 0.82 | ALDH1A1 (0.57) | GRM8GRM4ALDH1A1APPGAA | |
| Lysine SCHEMBL28059210 | 0.82 | ALDH1A1 (0.57) | GRM8GRM4ALDH1A1APPGAA | |
| SCHEMBL9219567 | 0.82 | GRM8 (0.46) | GRM8GRM4ALDH1A1APPGAA | |
| SCHEMBL10592278 | 0.81 | GRM8 (0.48) | GRM8GRM4ALDH1A1PLOD2NOS1 | |
| SCHEMBL9755838 | 0.81 | GRM8 (0.48) | GRM8GRM4ALDH1A1PLOD2NOS1 | |
| SCHEMBL2238928 | 0.81 | EPHX2 (0.70) | ALDH1A1EPHX2CYP2C9CYP2C19THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10815248-B2 | Labeled chemically reactive and biologically active conjugates, and methods and compositions thereof | SUN YI (US) | 2020-10-27 | — | — | US | disclosed |
| US-10226416-B2 | Hair conditioning composition for permanent and semi-permanent hair coloration applications | CLARIANT INTERNATIONAL LTD. (CH) | 2019-03-12 | — | — | US | disclosed |
| US-20180258099-A1 | NOVEL LABELED CHEMICALLY REACTIVE AND BIOLOGICALLY ACTIVE COMJUGATES, AND METHODS AND COMPOSITIONS THEREOF | SUN YI (US) | 2018-09-13 | — | — | US | disclosed |
| EP-3367096-A1 | DETECTION OF INTRACELLULAR BINDING EVENTS BY MEASURING PROTEIN ABUNDANCE | DiscoveRx Corporation (US) | 2018-08-29 | — | — | EP | disclosed |
| EP-2830583-B1 | HAIR CONDITIONING COMPOSITION FOR PERMANENT AND SEMI-PERMANENT HAIR COLORATION APPLICATIONS | CLARIANT INT LTD (CH) | 2018-05-23 | — | — | EP | disclosed |
| US-9951085-B2 | Labeled chemically reactive and biologically active comjugates, and methods and compositions thereof | SUN YI (US) | 2018-04-24 | — | — | US | disclosed |
| US-20180099997-A1 | VIBRO-BASED DELIVERY SYSTEM AND IMMUNE SUPPRESSION | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2018-04-12 | — | — | US | disclosed |
| US-9845341-B2 | Vibro-based delivery system and immune suppression | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-12-19 | — | — | US | disclosed |
| US-9828393-B2 | Silylalkyloxyaryl compounds and methods for treating cancer | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2017-11-28 | — | — | US | disclosed |
| US-9388449-B2 | Monitoring protein trafficking using beta-galactosidase reporter fragment complementation | DISCOVERX CORPORATION (US) | 2016-07-12 | — | — | US | disclosed |
| WO-2001043871-A2 | MICROARRAY HYBRIDIZATION CHAMBER | INCYTE GENOMICS, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
| EP-1105404-A1 | PURIFICATION OF OLIGOMERS USING DUAL-END SELECTION | Bayer Corporation (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6186659-B1 | Apparatus and method for mixing a film of fluid | AGILENT TECHNOLOGIES INC. | 2001-02-13 | — | — | US | disclosed |
| EP-1062230-A1 | METHOD FOR INCREASING THE SERUM HALF-LIFE OF A BIOLOGICALLY ACTIVE MOLECULE | Chiron Corporation (US) | 2000-12-27 | — | — | EP | disclosed |
| WO-2000026262-A2 | FUNCTIONALIZED POLYMERIC SUBSTRATES FOR BINDING MOLECULAR MOIETIES | MITOKOR (US) | 2000-05-11 | — | — | WO | disclosed |
| WO-2000012524-A1 | PURIFICATION OF OLIGOMERS USING DUAL-END SELECTION | BAYER CORPORATION (US) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000011022-A1 | ANTI-CANCER COMPOUNDS AND METHODS RELATED THERETO | STEWART JOHN M (US) | 2000-03-02 | — | — | WO | disclosed |
| WO-1999045026-A1 | METHOD FOR INCREASING THE SERUM HALF-LIFE OF A BIOLOGICALLY ACTIVE MOLECULE | CHIRON CORPORATION (US) | 1999-09-10 | — | — | WO | disclosed |
| US-5840835-A | MAJOR HISTOCOMPATIBILITY COMPLEX; USED IN THE TREATMENT AND PREVENTION OF AUTOIMMUNE DISEASES | MERCK & CO., INC. (US) | 1998-11-24 | — | — | US | disclosed |
| WO-1997016188-A1 | NOVEL INHIBITORS OF PEPTIDE BINDING TO MHC CLASS II PROTEINS | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180258099-A1 | NOVEL LABELED CHEMICALLY REACTIVE AND BIOLOGICALLY ACTIVE COMJUGATES, AND METHODS AND COMPOSITIONS THEREOF | CD44, GUSB, PAICS | GRM8 3542/4885GRM4 4175/4885ALDH1A1 543/4885 |
| US-10815248-B2 | Labeled chemically reactive and biologically active conjugates, and methods and compositions thereof | GUSB, PAICS, CD44 | GRM8 3752/4885GRM4 4260/4885ALDH1A1 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.