Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755879 | 0.99 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1HPGDKDM4E | |
| SCHEMBL9755842 | 0.99 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1HPGDKDM4E | |
| SCHEMBL9756355 | 0.99 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1HPGDKDM4E | |
| SCHEMBL9756077 | 0.98 | HPGD (0.49) | SMN1; SMN2KMT2AMEN1HPGDABCB1 | |
| SCHEMBL9755860 | 0.95 | ABCB1 (0.49) | ABCB1 | |
| SCHEMBL9755927 | 0.81 | MEN1 (0.48) | SMN1; SMN2KMT2AMEN1ABCB1 | |
| SCHEMBL9714501 | 0.80 | ABCB1 (0.60) | ABCB1 | |
| SCHEMBL9755913 | 0.80 | ABCB1 (0.51) | ABCB1 | |
| SCHEMBL9755884 | 0.80 | KMT2A (0.50) | SMN1; SMN2KMT2AMEN1ABCB1 | |
| SCHEMBL9755843 | 0.80 | KMT2A (0.50) | SMN1; SMN2KMT2AMEN1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |