Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756050 | 0.92 | HPGD (0.49) | LMNAABCB1CTSD | |
| SCHEMBL9756165 | 0.88 | HPGD (0.50) | LMNAABCB1CTSD | |
| SCHEMBL9756329 | 0.84 | CTSD (0.48) | ABCB1CTSD | |
| SCHEMBL9755900 | 0.84 | TP53 (0.52) | LMNAABCB1CTSD | |
| SCHEMBL9755953 | 0.84 | HDAC1 (0.45) | LMNAABCB1 | |
| SCHEMBL9756089 | 0.83 | CTSD (0.47) | ABCB1CTSD | |
| SCHEMBL9756028 | 0.83 | CTSD (0.47) | ABCB1CTSD | |
| SCHEMBL9756127 | 0.83 | CTSD (0.47) | ABCB1CTSD | |
| SCHEMBL9755948 | 0.83 | CTSD (0.47) | ABCB1CTSD | |
| SCHEMBL9755942 | 0.83 | POLB (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |