Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11411747 | 0.90 | MAPT (0.53) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL29376940 | 0.87 | MAPT (0.61) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL30534024 | 0.87 | MAPT (0.61) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL127064 | 0.87 | MAPT (0.61) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| Ethametsulfuron Methyl SCHEMBL15019468 | 0.83 | MAPT (0.56) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11377675 | 0.82 | CDK1 (0.46) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9756352 | 0.79 | CDK1 (0.43) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11384234 | 0.79 | CDK1 (0.41) | MAPTCDK1 | |
| SCHEMBL11370910 | 0.79 | GAA (0.45) | MAPTKDM4ENPC1SMN1; SMN2CDK1 | |
| SCHEMBL987342 | 0.78 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004967-A1 | COMPOUNDS USEFUL FOR MEASURING LOW LEVELS OF SULFONYLUREAS BY IMMUNOASSAY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-18 | — | — | WO | disclosed |