SCHEMBL9756250

SCHEMBL9756250

COC(=O)Cc1c[nH]c2ccc(Cl)c(Cl)c12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 2/20 0.43
PKM P14618 1/20 0.40
ALDH1A1 P00352 3/20 0.39
GAA P10253 3/20 0.39
MAPT P10636 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
KDM4E B2RXH2 2/20 0.39
POLB P06746 1/20 0.39
THRB P10828 1/20 0.39
DNMT1 P26358 1/20 0.39
RECQL P46063 1/20 0.39
CASP6 P55212 1/20 0.39
MCL1 Q07820 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 4/20 0.38
NPSR1 Q6W5P4 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MTNR1A P48039 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27554482 0.87 NR4A2 (0.41) NR4A2PKMALDH1A1GAAMAPT
SCHEMBL152993 0.84 NR4A2 (0.59) NR4A2PKMALDH1A1GAAMAPT
SCHEMBL9755961 0.81 ALDH1A1 (0.58) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL31750327 0.78 NR4A2 (0.52) NR4A2PKMALDH1A1GAAMAPT
SCHEMBL9755930 0.77 CSNK2A2 (0.48) NR4A2ALDH1A1GAAMAPTMEN1
SCHEMBL13555146 0.75 ALDH1A1 (0.48) NR4A2PKMALDH1A1GAAMAPT
SCHEMBL3560986 0.75 ALDH1A1 (0.48) NR4A2PKMALDH1A1GAAMAPT
SCHEMBL20769666 0.75 MTNR1A (0.60) NR4A2MEN1KMT2AKDM4EMTNR1A
SCHEMBL13083665 0.75 GAA (0.50) NR4A2PKMALDH1A1GAAMAPT
SCHEMBL9937273 0.75 LRRK2 (0.47) NR4A2PKMALDH1A1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0256128-B1 INDOLEACETIC ACID DERIVATIVES AND USE THEREOF AS PLANT GROWTH REGULATORS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-11-06 EP disclosed
US-4806143-A Indoleacetic acid derivatives and application thereof as plant growth regulators NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1989-02-21 US disclosed
EP-0256128-A1 INDOLEACETIC ACID DERIVATIVES AND USE THEREOF AS PLANT GROWTH REGULATORS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1988-02-24 EP disclosed