Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756406 | 0.99 | ABCB1 (0.40) | ABCB1PTGS2 | |
| SCHEMBL9755935 | 0.97 | ABCB1 (0.41) | ABCB1NPC1CTSD | |
| SCHEMBL9756139 | 0.92 | ABCB1 (0.43) | ABCB1NPC1CTSD | |
| SCHEMBL9756218 | 0.88 | ABCB1 (0.44) | ABCB1NPC1CTSD | |
| SCHEMBL9756469 | 0.83 | CTSD (0.43) | ABCB1PTGS2CTSD | |
| SCHEMBL9756408 | 0.82 | CTSD (0.42) | ABCB1PTGS2CTSD | |
| SCHEMBL9755951 | 0.82 | POLB (0.53) | — | |
| SCHEMBL9756326 | 0.81 | HDAC8 (0.49) | — | |
| SCHEMBL9756455 | 0.81 | POLB (0.52) | — | |
| SCHEMBL9755901 | 0.81 | HDAC8 (0.42) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |