Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387626 | 0.81 | NOTUM (0.56) | NOTUMCYP19A1ALDH1A1 | |
| SCHEMBL4484833 | 0.81 | NOTUM (0.56) | NOTUMCYP19A1PTGS1LMNAAKR1C3 | |
| SCHEMBL12794021 | 0.80 | NOTUM (1.00) | NOTUMCYP19A1ALDH1A1 | |
| SCHEMBL10287707 | 0.78 | ALDH1A1 (0.69) | NOTUMLMNABLMSMN1; SMN2MEN1 | |
| SCHEMBL11495989 | 0.78 | POLB (0.50) | NOTUMPTGS2PTGS1LMNACYP2C9 | |
| SCHEMBL18865691 | 0.77 | NOTUM (0.74) | NOTUMCYP19A1ALDH1A1 | |
| SCHEMBL462839 | 0.75 | NOTUM (0.56) | NOTUMCYP19A1TSHRTP53MEN1 | |
| SCHEMBL17984479 | 0.74 | NOTUM (0.48) | NOTUMCYP19A1ELOVL1TP53MEN1 | |
| SCHEMBL20546645 | 0.74 | NOTUM (0.48) | NOTUMCYP19A1ELOVL1TP53MEN1 | |
| SCHEMBL59197 | 0.73 | PTGS2 (0.74) | PTGS2PTGS1LMNACYP2C9AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432212-A1 | HERBICIDAL TRIAZOLINONES. | FMC CORP (US) | 1991-06-19 | — | — | EP | disclosed |
| WO-1990002120-A1 | HERBICIDAL TRIAZOLINONES | FMC CORPORATION (US) | 1990-03-08 | — | — | WO | disclosed |