Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756747 | 1.00 | HMGCR (0.48) | HMGCR | |
| SCHEMBL9756785 | 0.84 | HMGCR (0.56) | HMGCR | |
| SCHEMBL10640337 | 0.79 | HMGCR (0.70) | HMGCR | |
| SCHEMBL10640328 | 0.79 | HMGCR (0.70) | HMGCR | |
| SCHEMBL10335175 | 0.79 | HMGCR (0.42) | HMGCR | |
| SCHEMBL10335174 | 0.79 | HMGCR (0.42) | HMGCR | |
| SCHEMBL9756864 | 0.78 | HMGCR (0.38) | HMGCR | |
| SCHEMBL9756865 | 0.78 | HMGCR (0.38) | HMGCR | |
| SCHEMBL9756772 | 0.77 | HMGCR (0.48) | HMGCR | |
| SCHEMBL9764105 | 0.77 | MEN1 (0.39) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992462-A | Inhibitor of HMG-CoA reductase | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |