Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729043 | 0.86 | MAPT (0.45) | MAPTKCNN4SRCPDK1PDK2 | |
| SCHEMBL28531503 | 0.84 | MAPT (0.59) | MAPTKCNN4SRCELANETSHR | |
| SCHEMBL19707373 | 0.82 | RAB9A (0.53) | MAPTTP53ALDH1A1CYP26A1 | |
| SCHEMBL28229440 | 0.82 | MAPT (0.57) | MAPTKCNN4SRCELANETSHR | |
| SCHEMBL2986775 | 0.82 | MAPT (0.56) | MAPTTSHRHSD17B10SMN1; SMN2NPSR1 | |
| SCHEMBL1646972 | 0.81 | NAPRT (0.46) | MAPTTSHRNAPRTHSD17B10HDAC3 | |
| SCHEMBL11350456 | 0.81 | NAPRT (0.52) | MAPTTSHRNAPRTHSD17B10PDK1 | |
| SCHEMBL11333348 | 0.81 | ELANE (0.48) | MAPTELANETSHRPDK1PDK2 | |
| SCHEMBL19707314 | 0.81 | POLB (0.54) | MAPTELANETSHRPDK1PDK2 | |
| SCHEMBL5955245 | 0.80 | RAB9A (0.62) | MAPTSMN1; SMN2ALDH1A1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041518-A | Process for the production of polyhydantoins containing amide groups and/or imide groups | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |
| US-5006641-A | Heat resistance, construction materials, cyclization of polyureas | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |