SCHEMBL1646972

SCHEMBL1646972

CC(C)(Nc1ccccc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MAPT P10636 5/20 0.46
TSHR P16473 2/20 0.44
TP53 P04637 1/20 0.44
EPHX1 P07099 1/20 0.44
EPHX2 P34913 1/20 0.44
CDK9 P50750 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
PDK1 Q15118 2/20 0.44
PDK2 Q15119 2/20 0.44
PDK3 Q15120 2/20 0.44
PDK4 Q16654 2/20 0.44
CYP3A4 P08684 1/20 0.43
ALOX5 P09917 1/20 0.43
HSP90AA1 P07900 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
RAB9A P51151 2/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8791650 0.98 NAPRT (0.45) NAPRTHSD17B10MAPTTSHRTP53
SCHEMBL11350456 0.86 NAPRT (0.52) NAPRTHSD17B10MAPTTSHRTP53
SCHEMBL5954425 0.83 HPGD (0.49) MAPTSMN1; SMN2RAB9AHPGDNPC1
SCHEMBL5954995 0.83 HPGD (0.56) EPHX1SMN1; SMN2PDK1PDK2PDK3
SCHEMBL5954475 0.83 LMNA (0.49) POLB
SCHEMBL19707372 0.83 MAPT (0.47) MAPTSMN1; SMN2RAB9AHPGDNPC1
SCHEMBL3076892 0.83 MAPT (0.50) NAPRTHSD17B10MAPTTSHRTP53
SCHEMBL5514973 0.82 NAPRT (0.46) NAPRTHSD17B10MAPTTSHRTP53
SCHEMBL25041715 0.81 NR1H4 (0.51) MAPTEPHX2SMN1; SMN2PDK1PDK2
SCHEMBL9756879 0.81 MAPT (0.59) NAPRTHSD17B10MAPTTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106800536-A A kind of preparation method of the miscellaneous Shandong amine of grace 南京慧博生物科技有限公司 2017-06-06 CN claimed
EP-0012379-B1 LAQUER MIXTURE AND COATING MATERIAL CONTAINING POLYAMIDE HYDANTOINS BAYER AG (DE) 1983-06-01 EP claimed
EP-0012381-B1 PROCESS FOR THE PREPARATION OF COMPOUNDS CONTAINING HYDANTOIN GROUPS BAYER AG (DE) 1982-12-15 EP claimed
US-4281095-A Coating compositions obtained by reacting amino carboxylic acids derivatives with polyisocyanates and compounds containing carboxylic groups to produce polymers containing hydantoin rings and amide groups BAYER AKTIENGESELLSCHAFT (DE) 1981-07-28 US claimed
US-4269750-A Process for the preparation of polymers containing hydantoin groups BAYER AKTIENGESELLSCHAFT (DE) 1981-05-26 US claimed
EP-4681207-A2 METHODS FOR PREDICTING RESPONSE TO PHARMACOLOGICAL AGENTS IN PATIENTS WITH OBESITY Phenomix Sciences, Inc. (US) 2026-01-21 EP disclosed
EP-4680343-A1 PROTEIN-PROTEIN INTERACTION STABILIZERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-21 EP disclosed
US-20250319054-A1 Synthetic Eicosanoid Analogues for the Treatment and Prevention of Diseases Associated with Increased GDF15 Plasma Concentration OMEICOS THERAPEUTICS GMBH (DE) 2025-10-16 US disclosed
US-20250263393-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-08-21 US disclosed
EP-4590664-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-07-30 EP disclosed
US-12370158-B2 Analogs of CYP-eicosanoids for use in treating or preventing a disorder associated with neovascularization and/or inflammation OMEICOS THERAPEUTICS GMBH (DE) 2025-07-29 US disclosed
US-20250127937-A1 FAP INHIBITOR UNIV HEIDELBERG (DE) 2025-04-24 US disclosed
EP-0253007-A1 Stabilized polymers, novel stabilizers, and synthesis thereof The B.F. GOODRICH Company (US) 1988-01-20 EP disclosed
US-4601839-A A-AMINOACETAMIDES THE B. F. GOODRICH COMPANY (US) 1986-07-22 US disclosed
US-4466915-A Non-catalytic ketoform syntheses THE B. F. GOODRICH COMPANY (US) 1984-08-21 US disclosed
EP-0104645-A1 Non-catalytic ketoform syntheses The B.F. GOODRICH Company (US) 1984-04-04 EP disclosed
US-4310429-A HEAT AND OXIDATION RESISTANT AMINOACETAMIDES THE B. F. GOODRICH COMPANY (US) 1982-01-12 US disclosed
US-4281095-A Coating compositions obtained by reacting amino carboxylic acids derivatives with polyisocyanates and compounds containing carboxylic groups to produce polymers containing hydantoin rings and amide groups BAYER AKTIENGESELLSCHAFT (DE) 1981-07-28 US disclosed
US-4269750-A Process for the preparation of polymers containing hydantoin groups BAYER AKTIENGESELLSCHAFT (DE) 1981-05-26 US disclosed
EP-0007182-A1 Stabilized polymers, novel stabilizers and synthesis thereof The B.F. GOODRICH Company (US) 1980-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250319054-A1 Synthetic Eicosanoid Analogues for the Treatment and Prevention of Diseases Associated with Increased GDF15 Plasma Concentration IL15, ALOX15, FABP3 NAPRT 2791/4885HSD17B10 309/4885MAPT 4543/4885
US-20250127937-A1 FAP INHIBITOR FAP, APC, FIBP NAPRT 601/4885HSD17B10 2946/4885MAPT 1720/4885
US-20250263393-A1 FAP INHIBITORS FAP, APC, FIBP NAPRT 471/4885HSD17B10 2339/4885MAPT 2392/4885
US-12370158-B2 Analogs of CYP-eicosanoids for use in treating or preventing a disorder associated with neovascularization and/or inflammation ALOX5, ALOX15B, ALOX15 NAPRT 736/4885HSD17B10 100/4885MAPT 4420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.