Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.49 |
| ▸ | F9 | P00740 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757101 | 0.92 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2F9F10GPBAR1 | |
| SCHEMBL9757258 | 0.90 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL8801668 | 0.82 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL9756934 | 0.82 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL9757208 | 0.81 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL9757209 | 0.78 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2 | |
| SCHEMBL27393484 | 0.77 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL9757206 | 0.76 | NR4A2 (0.42) | CYSLTR1F9F10NR4A2MRGPRX4 | |
| SCHEMBL8325040 | 0.76 | CYSLTR1 (0.74) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL8131833 | 0.75 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2GPBAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |