Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.45 |
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756965 | 0.92 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2F9F10GPBAR1 | |
| SCHEMBL9756934 | 0.88 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL9757209 | 0.82 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL8801668 | 0.82 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 | |
| SCHEMBL9757716 | 0.81 | ALOX5AP (0.48) | CYSLTR1CYSLTR2ALOX5APPDE10A | |
| SCHEMBL9757206 | 0.81 | NR4A2 (0.42) | CYSLTR1F9F10TBXAS1NR4A2 | |
| SCHEMBL9757258 | 0.80 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL9757134 | 0.80 | CYSLTR1 (0.58) | CYSLTR1GPBAR1ALOX5APFFAR1AKR1B1 | |
| SCHEMBL9756941 | 0.79 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL9054127 | 0.78 | FFAR1 (0.55) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |