SCHEMBL9757005

SCHEMBL9757005

CCC(C[SiH](OC)OC)NCCCCN

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31
CNR1 P21554 1/20 0.31
ADRA1A P35348 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ABCC3 O15438 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA12 O43570 1/20 0.30
F13A1 P00488 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CYP1A2 P05177 1/20 0.30
CA3 P07451 1/20 0.30
CYP2C9 P11712 1/20 0.30
PKM P14618 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19549534 0.98 PAOX (0.31) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL549555 0.87 LMNA (0.34) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL16799175 0.84 LMNA (0.34) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL21409764 0.80 LMNA (0.37) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL15201448 0.79 LMNA (0.42) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL21799534 0.77 DNM1 (0.42) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL21799793 0.77 DNM1 (0.42) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL21799761 0.77 DNM1 (0.42) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL21799516 0.77 DNM1 (0.42) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL21799879 0.77 DNM1 (0.42) LMNACNR1ADRA1ATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5025049-A Organic copolymer containing alkoxysilylated monomer, polyalkyl (meth) acrylate, crosslinking agent and ultraviolet absorber SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-06-18 US disclosed