Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757138 | 0.93 | CYSLTR1 (0.40) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757167 | 0.86 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757140 | 0.86 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2 | |
| SCHEMBL9756989 | 0.81 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2 | |
| SCHEMBL9756995 | 0.81 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757170 | 0.79 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757187 | 0.78 | TEC (0.38) | CYSLTR1CYSLTR2KDM4ENPC1RAB9A | |
| SCHEMBL9757240 | 0.78 | TEC (0.38) | CYSLTR1CYSLTR2KDM4ENPC1RAB9A | |
| SCHEMBL13513030 | 0.75 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9757010 | 0.74 | RAB9A (0.40) | CYSLTR1CYSLTR2SMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |