Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757170 | 0.91 | CYSLTR1 (0.46) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757288 | 0.86 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757139 | 0.85 | CYSLTR1 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757159 | 0.81 | CYSLTR1 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757084 | 0.80 | CYSLTR1 (0.38) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757235 | 0.79 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757276 | 0.79 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL9756983 | 0.79 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757167 | 0.77 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757140 | 0.77 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |