Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757164 | 0.91 | NR4A2 (0.33) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757283 | 0.86 | CYSLTR1 (0.38) | CYSLTR1GPBAR1CYSLTR2CNR2 | |
| SCHEMBL9757139 | 0.84 | CYSLTR1 (0.50) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9757159 | 0.80 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757092 | 0.80 | CYSLTR2 (0.45) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757221 | 0.79 | CYSLTR1 (0.49) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9757264 | 0.79 | CYSLTR1 (0.49) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9756982 | 0.78 | FFAR1 (0.39) | CYSLTR1 | |
| SCHEMBL9757132 | 0.78 | FFAR1 (0.43) | — | |
| SCHEMBL9756999 | 0.78 | MAPT (0.35) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |