Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757231 | 0.92 | RAB9A (0.40) | CYSLTR2CYSLTR1 | |
| SCHEMBL9756989 | 0.91 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1TLR4TLR2 | |
| SCHEMBL9756995 | 0.91 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1TLR4TLR2 | |
| SCHEMBL9757276 | 0.86 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL9756983 | 0.86 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757092 | 0.86 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757010 | 0.85 | RAB9A (0.40) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757167 | 0.85 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1TLR4TLR2 | |
| SCHEMBL9757140 | 0.85 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1TLR4TLR2 | |
| SCHEMBL9757125 | 0.84 | CYSLTR1 (0.51) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |