Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 6/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757274 | 0.89 | TOP2A (0.57) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8094873 | 0.88 | TOP2A (0.60) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9757511 | 0.87 | TOP2A (0.56) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9757420 | 0.87 | TOP2A (0.56) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9757498 | 0.87 | TOP2A (0.56) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9757089 | 0.85 | TOP2A (0.54) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9757546 | 0.85 | KDM4E (0.52) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9757408 | 0.85 | KCNH2 (0.55) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9757365 | 0.85 | CACNA1F (0.61) | KCNH2POLBTOP2ATOP2BGSK3B | |
| SCHEMBL9757327 | 0.84 | KDM4E (0.57) | ALDH1A1KDM4EHPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |