Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 6/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757334 | 0.90 | TOP2A (0.56) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9757349 | 0.89 | TOP2A (0.56) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9757256 | 0.88 | TOP2A (0.53) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL8093551 | 0.88 | TOP2A (0.53) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9757337 | 0.88 | TOP2A (0.53) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL8094873 | 0.87 | TOP2A (0.60) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9757471 | 0.87 | MEN1 (0.59) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9757384 | 0.86 | TOP2A (0.52) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9757502 | 0.85 | KCNH2 (0.53) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9757121 | 0.85 | KCNH2 (0.54) | KDM4EKCNH2HPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |