Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEC | P42680 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757146 | 0.81 | TEC (0.37) | TECCYSLTR2CYSLTR1 | |
| SCHEMBL9757175 | 0.81 | TEC (0.37) | TECMAOBCYSLTR2CYSLTR1RXRA | |
| SCHEMBL9757075 | 0.81 | ROCK1 (0.32) | MAOB | |
| SCHEMBL9757206 | 0.80 | NR4A2 (0.42) | TECMAOBCYSLTR1RXRARXRB | |
| SCHEMBL9757647 | 0.76 | MAOB (0.34) | MAOBCYSLTR2CYSLTR1NR4A2 | |
| SCHEMBL9757132 | 0.73 | FFAR1 (0.43) | MAOBNR4A2 | |
| SCHEMBL9756982 | 0.73 | FFAR1 (0.39) | MAOBCYSLTR1NR4A2 | |
| SCHEMBL9756999 | 0.71 | MAPT (0.35) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757222 | 0.71 | CYSLTR1 (0.35) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757104 | 0.71 | PDE10A (0.49) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |
| US-5041453-A | Quinolinyl-benzoheterobicyclic derivatives as antagonists of leukotriene D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |