Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637857 | 0.84 | HDAC1 (0.49) | HDAC1PKMALDH1A1POLBHTT | |
| SCHEMBL11773546 | 0.82 | PKM (0.61) | HDAC1PKMALDH1A1POLBHTT | |
| SCHEMBL9757496 | 0.80 | HDAC1 (0.54) | HDAC1PKMALDH1A1POLBKMT2A | |
| SCHEMBL9757292 | 0.79 | CA12 (0.49) | HDAC1PKMALDH1A1HTTKMT2A | |
| SCHEMBL7006375 | 0.78 | HDAC1 (0.57) | HDAC1PKMALDH1A1POLBHTT | |
| SCHEMBL382362 | 0.78 | HDAC1 (0.54) | HDAC1PKMALDH1A1POLBHTT | |
| SCHEMBL9757210 | 0.78 | HDAC1 (0.54) | HDAC1PKMALDH1A1POLBHTT | |
| SCHEMBL14640610 | 0.77 | RYR2 (0.65) | HDAC1PKMHTTKMT2AMEN1 | |
| SCHEMBL5708819 | 0.77 | GAA (0.62) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL14045768 | 0.75 | AKR1C3 (0.57) | ALDH1A1POLBKMT2ADRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |