Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773546 | 0.85 | PKM (0.61) | HDAC1KMT2AMEN1PKMLMNA | |
| SCHEMBL382362 | 0.82 | HDAC1 (0.54) | HDAC1KMT2AMEN1PKMGAA | |
| SCHEMBL7006375 | 0.82 | HDAC1 (0.57) | HDAC1KMT2AMEN1PKMTHRB | |
| SCHEMBL14640610 | 0.81 | RYR2 (0.65) | HDAC1KMT2AMEN1PKMLMNA | |
| SCHEMBL5708819 | 0.80 | GAA (0.62) | KMT2AMEN1PKMLMNAGAA | |
| SCHEMBL7497005 | 0.79 | HDAC1 (0.49) | HDAC1KMT2AMEN1PKMLMNA | |
| SCHEMBL9757230 | 0.78 | HDAC1 (0.51) | HDAC1KMT2AMEN1PKMGAA | |
| SCHEMBL1266856 | 0.77 | ESR1 (0.49) | HDAC1KMT2AMEN1AKR1C3 | |
| SCHEMBL9602776 | 0.77 | PKM (0.64) | KMT2AMEN1PKMLMNAGAA | |
| SCHEMBL16637857 | 0.76 | HDAC1 (0.49) | HDAC1PKMLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |