Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22179161 | 0.85 | HPGD (0.55) | MAPTHPGDPABPC1ALOX15MAPK1 | |
| SCHEMBL31328966 | 0.85 | MAPT (0.55) | MAPTHPGDPABPC1ALOX15MAPK1 | |
| SCHEMBL10928006 | 0.85 | ALOX15 (0.56) | MAPTHPGDPABPC1ALOX15MAPK1 | |
| SCHEMBL30059684 | 0.85 | KMT2A (0.56) | MAPTHPGDPABPC1ALOX15MAPK1 | |
| SCHEMBL31689407 | 0.85 | HPGD (0.55) | MAPTHPGDPABPC1ALOX15MAPK1 | |
| SCHEMBL3250733 | 0.85 | KMT2A (0.56) | MAPTHPGDPABPC1ALOX15MAPK1 | |
| SCHEMBL1833283 | 0.85 | MAPK1 (0.55) | MAPTHPGDPABPC1ALOX15MAPK1 | |
| SCHEMBL21996377 | 0.85 | CASP3 (0.55) | MAPTHPGDPABPC1ALOX15MAPK1 | |
| SCHEMBL24422407 | 0.84 | HPGD (0.53) | MAPTHPGDPABPC1ALOX15MAPK1 | |
| SCHEMBL18974146 | 0.83 | CES1 (0.66) | MAPTHPGDALOX15HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204380-B1 | NOVEL AMINOPYRIDINE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN PRENYLATION | INST NAT SANTE RECH MED (FR) | 2019-08-07 | — | — | EP | disclosed |
| US-9777320-B2 | Molecular adaptors for dye conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |