Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757501 | 0.86 | HPGD (0.56) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9757328 | 0.86 | TOP2A (0.50) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9757048 | 0.85 | DRD3 (0.61) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL9757249 | 0.85 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9757405 | 0.85 | PIM1 (0.49) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9757476 | 0.84 | TOP1 (0.50) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL313584 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9757695 | 0.79 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11073382 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9757327 | 0.76 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |