Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.63 |
| ▸ | HPGD | P15428 | 7/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313584 | 0.93 | KDM4E (0.61) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9757501 | 0.89 | HPGD (0.56) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9757327 | 0.87 | KDM4E (0.57) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9757390 | 0.86 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9757350 | 0.85 | KDM4E (0.53) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL312380 | 0.85 | KDM4E (0.84) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL11185030 | 0.84 | KDM4E (0.71) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL312663 | 0.83 | KDM4E (0.70) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10739914 | 0.83 | KDM4E (0.70) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL8094873 | 0.82 | TOP2A (0.60) | KDM4EHPGDHSD17B10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |