Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 4/20 | 0.42 |
| ▸ | TOP2A | P11388 | 4/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757293 | 0.92 | LMNA (0.50) | PIM1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9757148 | 0.90 | LMNA (0.49) | PIM1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9757156 | 0.90 | TOP2A (0.47) | LMNAMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL9757333 | 0.90 | LMNA (0.50) | PIM1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9757331 | 0.90 | LMNA (0.48) | PIM1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9757188 | 0.89 | HPGD (0.55) | PIM1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9757261 | 0.89 | LMNA (0.49) | PIM1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9757512 | 0.87 | KDM4E (0.47) | PIM1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9757405 | 0.86 | PIM1 (0.49) | PIM1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9757351 | 0.85 | TOP1 (0.50) | PIM1LMNAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |