Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | PIM1 | P11309 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 3/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757315 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9757261 | 0.90 | LMNA (0.49) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9757293 | 0.90 | LMNA (0.50) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9757148 | 0.88 | LMNA (0.49) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9757372 | 0.87 | PIM1 (0.48) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9757331 | 0.87 | LMNA (0.48) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9757333 | 0.87 | LMNA (0.50) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9757188 | 0.87 | HPGD (0.55) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9757467 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9757405 | 0.84 | PIM1 (0.49) | KDM4EALDH1A1POLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |