Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335753 | 0.83 | DDB1 (0.50) | TAS1R3TAS1R1TAS1R2MAPTALDH1A1 | |
| SCHEMBL8422243 | 0.79 | DPP8 (0.59) | KDM4EMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL9757421 | 0.77 | KMT2A (0.46) | KDM4EMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL6677698 | 0.76 | NOTUM (0.57) | MAPTSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL6341159 | 0.76 | HPGD (0.51) | TAS1R3TAS1R1TAS1R2MAPTSMN1; SMN2 | |
| SCHEMBL16099710 | 0.76 | ACHE (0.50) | TAS1R3TAS1R1TAS1R2ALDH1A1KMT2A | |
| SCHEMBL8331252 | 0.75 | MAPT (0.45) | TAS1R3TAS1R1TAS1R2MAPTSMN1; SMN2 | |
| SCHEMBL14287212 | 0.73 | MAPT (0.48) | KDM4EMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17197559 | 0.73 | UCHL1 (0.52) | TAS1R3TAS1R1TAS1R2MAPTALDH1A1 | |
| SCHEMBL31335848 | 0.73 | HSP90AA1 (0.54) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |