Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quazepam SCHEMBL29504 | 0.90 | OPRK1 (0.58) | OPRK1NR1I2ADORA3OPRM1TP53 | |
| Quazepam SCHEMBL29534458 | 0.90 | OPRK1 (0.58) | OPRK1NR1I2ADORA3OPRM1TP53 | |
| Quazepam SCHEMBL21647120 | 0.89 | OPRK1 (0.57) | OPRK1NR1I2ADORA3OPRM1TP53 | |
| Quazepam SCHEMBL28142863 | 0.79 | PTAFR (0.61) | OPRK1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7873579 | 0.78 | OPRK1 (0.48) | OPRK1NR1I2ADORA3OPRM1TP53 | |
| SCHEMBL11804705 | 0.78 | TP53 (0.52) | OPRK1TP53LMNAGABRA1GABRG2 | |
| Quazepam SCHEMBL3177949 | 0.77 | OPRK1 (0.45) | OPRK1NR1I2ADORA3OPRM1TP53 | |
| SCHEMBL5379874 | 0.77 | OPRK1 (0.77) | OPRK1NR1I2ADORA3OPRM1TP53 | |
| SCHEMBL13531318 | 0.76 | OPRK1 (0.62) | OPRK1NR1I2ADORA3OPRM1TP53 | |
| Quazepam SCHEMBL1181404 | 0.76 | OPRK1 (0.66) | OPRK1NR1I2ADORA3OPRM1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3169816-A | — | — | None | — | — | JP | disclosed |
| JP-H03169816-A | ORAL ADMINISTRATION OF TRIFLUOROBENZODIAZEPINES | ELLINWOOD JR EVERETT H | 1991-07-23 | — | — | JP | disclosed |