Trimethylammonium

Trimethylammonium

SCHEMBL9757620

CN(C)C.Cc1ccc(CCl)cc1

nearest known ligand 0.46

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.46
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PYCR1 P32322 1/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
AGXT P21549 2/20 0.41
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
KCNH2 Q12809 1/20 0.37
CHRNA7 P36544 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL27788339 0.97 IDO1 (0.44) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL45443 0.92
SCHEMBL3130646 0.89 IDO1 (0.50) IDO1CYP1A2CYP2A6TAAR1ACHE
Trimethylammonium SCHEMBL10702662 0.89 IDO1 (0.38) IDO1CYP1A2CYP2A6TAAR1ACHE
Methoxymethane SCHEMBL27696982 0.84 AGXT (0.46) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL8993222 0.84 IDO1 (0.46) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL9023183 0.84 IDO1 (0.46) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL5617928 0.83 ALDH1A1 (0.42) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL28574743 0.82 RAB9A (0.52) IDO1TAAR1ACHEALDH1A1TP53
Alcohol SCHEMBL28452318 0.82 IDO1 (0.44) IDO1CYP1A2CYP2A6TAAR1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3206056-A None JP disclosed
JP-H03206056-A PRODUCTION OF DICHLORO-(2,2)-PARACYCLOPHANE DAISAN KASEI KK 1991-09-09 JP disclosed
EP-0294651-B1 PROCESS FOR THE PREPARATION OF (2,2)-PARACYCLOPHANE UNION CARBIDE CORPORATION (US) 1991-02-27 EP disclosed
EP-0294651-A1 Process for the preparation of (2,2)-paracyclophane UNION CARBIDE CORPORATION (US) 1988-12-14 EP disclosed