Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.76 |
| ▸ | DRD3 | P35462 | 4/20 | 0.76 |
| ▸ | DRD4 | P21917 | 3/20 | 0.76 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559091 | 0.91 | DRD2 (0.84) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL9558839 | 0.90 | CHRM2 (0.68) | DRD2DRD3DRD4HTR1ACHRM2 | |
| SCHEMBL9558543 | 0.84 | DRD2 (0.68) | DRD2DRD3DRD4HTR1ACHRM2 | |
| SCHEMBL9717289 | 0.84 | DRD2 (0.68) | DRD2DRD3DRD4HTR1ACHRM2 | |
| SCHEMBL31208114 | 0.84 | DRD2 (0.75) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL31208122 | 0.84 | DRD2 (0.75) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL31208115 | 0.84 | DRD2 (0.75) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL11388217 | 0.84 | DRD2 (1.00) | DRD2DRD3DRD4HTR1A | |
| Hydrochloric Acid SCHEMBL9359305 | 0.83 | DRD2 (0.97) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL7384337 | 0.82 | DRD2 (0.77) | DRD2DRD3DRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407416-A1 | THERAPEUTICALLY USEFUL TETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1991-01-16 | — | — | EP | claimed |
| WO-1989009050-A1 | THERAPEUTICALLY USEFUL TETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1989-10-05 | — | — | WO | claimed |
| EP-0334538-A1 | Therapeutically useful tetralin derivatives | THE UPJOHN COMPANY (US) | 1989-09-27 | — | — | EP | claimed |