Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183287 | 1.00 | DNM1 (0.44) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL5541342 | 0.90 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL9620639 | 0.90 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL3295731 | 0.90 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL3296101 | 0.90 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL9620474 | 0.90 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL18291050 | 0.90 | — | — | |
| SCHEMBL3297653 | 0.90 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL7704071 | 0.90 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL3299577 | 0.87 | DNM1 (0.43) | DNM1TSHRTHRBZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992200-A | Of silver and gold as complexes of a guanidine compoumd | HENKEL CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4895597-A | ION EXCHANGE WITH GUANIDINE FUNCTIONALITY | HENKEL CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |
| US-4814007-A | SOLVENT EXTRACTION, GUANIDINE COMPOUND | HENKEL CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |