Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620639 | 1.00 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL3297653 | 1.00 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL7704071 | 1.00 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL9620474 | 1.00 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL3295731 | 1.00 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL3296101 | 1.00 | DNM1 (0.48) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL3299577 | 0.97 | DNM1 (0.43) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL11510525 | 0.95 | DNM1 (0.42) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL11511182 | 0.95 | DNM1 (0.42) | DNM1TSHRTHRBZDHHC20ZDHHC2 | |
| SCHEMBL8183287 | 0.90 | DNM1 (0.44) | DNM1TSHRTHRBZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269546-B1 | CYANAMIDE DERIVATIVES AS VULCANIZATION RATE MODIFIERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-01-02 | — | — | EP | claimed |
| EP-0269546-A1 | Cyanamide derivatives as vulcanization rate modifiers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-06-01 | — | — | EP | claimed |
| US-4714742-A | Cyanamide derivatives as vulcanization rate modifiers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-12-22 | — | — | US | claimed |
| EP-1806350-A2 | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents | BRACCO International B.V. (NL) | 2007-07-11 | — | — | EP | disclosed |
| EP-1153029-B1 | AMPHIPATIC POLYCARBOXYLIC CHELATES AND COMPLEXES WITH PARAMAGNETIC METALS AS MRI CONTRAST AGENTS | BRACCO INT BV (NL) | 2007-01-10 | — | — | EP | disclosed |
| US-6652834-B2 | Tensioactive properties, long lasting activity in the blood pool | BRACCO INTERNATIONAL B.V. (NL) | 2003-11-25 | — | — | US | disclosed |
| US-20020098152-A1 | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents | BRACCO INTERNATIONAL B.V. | 2002-07-25 | — | — | US | disclosed |
| US-6342598-B1 | BLOOD-POOL CONTRAST AGENTS OF OUTSTANDING LONG LIFE IN CIRCULATION | BRACCO INTERNATIONAL B.V. (NL) | 2002-01-29 | — | — | US | disclosed |
| EP-1153029-A2 | AMPHIPATIC POLYCARBOXYLIC CHELATES AND COMPLEXES WITH PARAMAGNETIC METALS AS MRI CONTRAST AGENTS | BRACCO INTERNATIONAL B.V. (NL) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000030688-A2 | AMPHIPATIC POLYCARBOXYLIC CHELATES AND COMPLEXES WITH PARAMAGNETIC METALS AS MRI CONTRAST AGENTS | BRACCO INTERNATIONAL B.V. (NL) | 2000-06-02 | — | — | WO | disclosed |
| EP-0269546-B1 | CYANAMIDE DERIVATIVES AS VULCANIZATION RATE MODIFIERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-01-02 | — | — | EP | disclosed |
| EP-0269546-A1 | Cyanamide derivatives as vulcanization rate modifiers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-06-01 | — | — | EP | disclosed |
| US-4714742-A | Cyanamide derivatives as vulcanization rate modifiers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020098152-A1 | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents | SLC39A14, HAMP, PICALM | DNM1 266/4885TSHR 1563/4885THRB 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.