Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 11/20 | 0.52 |
| ▸ | CDC7 | O00311 | 3/20 | 0.52 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.52 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17766765 | 0.93 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MEN1CYP1A2CYP2C9 | |
| SCHEMBL16391928 | 0.87 | ALDH1A1 (0.51) | ALDH1A1HSD17B10MEN1CYP1A2CYP2C9 | |
| SCHEMBL975465 | 0.84 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MEN1CYP1A2CYP2C9 | |
| SCHEMBL12922068 | 0.82 | CDC7 (0.47) | ALDH1A1HSD17B10KMT2AHPGDCDC7 | |
| SCHEMBL975813 | 0.82 | L3MBTL1 (0.48) | ALDH1A1HSD17B10MEN1KMT2AHPGD | |
| SCHEMBL19362086 | 0.81 | DHODH (0.60) | ALDH1A1HSD17B10MEN1CYP1A2CYP2C9 | |
| SCHEMBL18019812 | 0.81 | BTK (0.52) | ALDH1A1HSD17B10MEN1KMT2AHPGD | |
| SCHEMBL16597585 | 0.79 | BTK (0.72) | ALDH1A1HSD17B10MEN1CYP1A2CYP2C9 | |
| SCHEMBL17775919 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MEN1CYP1A2CYP2C9 | |
| SCHEMBL18017496 | 0.78 | BTK (0.70) | ALDH1A1HSD17B10MEN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162787-A1 | SEMI-ELECTROACTIVE MATERIAL CONTAINING ORGANIC COMPOUNDS WITH POSITIVE OR NEGATIVE REDOX ACTIVITY, METHOD AND KIT FOR MAKING SUCH MATERIAL, ELECTRICALLY CONTROLLED DEVICE AND GLAZING USING SUCH SEMI-ELECTROACTIVE MATERIAL | Saint-Gobain Glass France (FR) | 2010-03-17 | — | — | EP | claimed |
| WO-2009007602-A1 | SEMI-ELECTROACTIVE MATERIAL CONTAINING ORGANIC COMPOUNDS WITH POSITIVE OR NEGATIVE REDOX ACTIVITY, METHOD AND KIT FOR MAKING SUCH MATERIAL, ELECTRICALLY CONTROLLED DEVICE AND GLAZING USING SUCH SEMI-ELECTROACTIVE MATERIAL | SAINT-GOBAIN GLASS FRANCE (FR) | 2009-01-15 | — | — | WO | claimed |
| US-8673911-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2014-03-18 | — | — | US | disclosed |
| US-8673911-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2014-03-18 | — | — | US | disclosed |
| US-8673911-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2014-03-18 | — | — | US | disclosed |
| US-20140045850-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2014-02-13 | — | — | US | disclosed |
| US-20140045850-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2014-02-13 | — | — | US | disclosed |
| US-20140045850-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2014-02-13 | — | — | US | disclosed |
| EP-2539765-A1 | MATERIAL IMPREGNATED WITH AN ELECTROLYTE | Saint-Gobain Glass France (FR) | 2013-01-02 | — | — | EP | disclosed |
| US-20110021771-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2011-01-27 | — | — | US | disclosed |
| US-20110021771-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2011-01-27 | — | — | US | disclosed |
| US-20110021771-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2011-01-27 | — | — | US | disclosed |
| EP-2217588-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009055917-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2009-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021771-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC11, HDAC3 | ALDH1A1 699/4885HSD17B10 527/4885MEN1 3189/4885 |
| US-20140045850-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC11, HDAC3 | ALDH1A1 699/4885HSD17B10 527/4885MEN1 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.