Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9759279 | 0.99 | LMNA (0.43) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL9334774 | 0.92 | BCHE (0.41) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL9784924 | 0.91 | LMNA (0.35) | LMNATP53MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9784980 | 0.90 | LMNA (0.35) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL9331559 | 0.89 | LMNA (0.57) | LMNATP53MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9759697 | 0.89 | BCHE (0.42) | LMNATP53MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9331386 | 0.88 | LMNA (0.56) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL9504338 | 0.88 | LMNA (0.56) | LMNATP53MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9784877 | 0.87 | HTR1A (0.34) | LMNAMAPTMEN1KMT2ACHRM2 | |
| SCHEMBL9334180 | 0.86 | BCHE (0.39) | LMNAMAPTMEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049669-A | Also diuretics | RHONE-POULENC SANTE (FR) | 1991-09-17 | — | — | US | disclosed |
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |