Pronamide

Pronamide

SCHEMBL9759366

C#CC(C)(C)NC(=O)c1cc(Cl)cc(Cl)c1.NNC(=O)/C=C\C(=O)NN

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANO1 Q5XXA6 6/20 0.40
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
PKM P14618 1/20 0.39
GRN P28799 4/20 0.36
SORT1 Q99523 4/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
GAA P10253 2/20 0.36
MAPT P10636 1/20 0.36
FLT1 P17948 1/20 0.34
FLT4 P35916 1/20 0.34
KDR P35968 1/20 0.34
HTT P42858 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CACNA1H O95180 1/20 0.33
CYP2D6 P10635 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pronamide SCHEMBL9759374 0.95 L3MBTL1 (0.40) ANO1RAB9ANPC1PKMGRN
Pronamide SCHEMBL55124 0.87 RAB9A (0.47) ANO1RAB9ANPC1PKMGRN
Pronamide SCHEMBL2045136 0.87 RAB9A (0.47) ANO1RAB9ANPC1PKMGRN
Pronamide SCHEMBL28474286 0.86 RAB9A (0.46) ANO1RAB9ANPC1PKMGRN
Pronamide SCHEMBL28338727 0.86 RAB9A (0.46) ANO1RAB9ANPC1PKMGRN
Pronamide SCHEMBL28908557 0.84 RAB9A (0.45) ANO1RAB9ANPC1PKMGRN
Pronamide SCHEMBL6470029 0.83 ANO1 (0.42) ANO1RAB9ANPC1PKMGRN
Pronamide SCHEMBL28937485 0.82 ANO1 (0.43) ANO1RAB9ANPC1PKMGRN
Pronamide SCHEMBL27931053 0.77 ANO1 (0.43) ANO1RAB9ANPC1PKMGRN
Pronamide SCHEMBL10711363 0.75 ANO1 (0.41) ANO1RAB9ANPC1PKMGRN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5028732-A Herbicidally active amino diphenyl ethers ROHM AND HAAS COMPANY (US) 1991-07-02 US disclosed
US-4937381-A Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitro-diphenyl ethers ROHM AND HAAS COMPANY (US) 1990-06-26 US disclosed
US-4806682-A Sulfonium salts of diphenyl ethers ROHM AND HAAS COMPANY (US) 1989-02-21 US disclosed
US-4693742-A Herbicidal hydroxyamino phosphonic acids and derivatives ROHM AND HASS COMPANY (US) 1987-09-15 US disclosed
US-4584014-A PREEMERGENCE HERBICIDES;CORN, WHEAT AND OATS ROHM AND HAAS COMPANY (US) 1986-04-22 US disclosed
US-4314844-A FUNGICIDES ROHM AND HAAS COMPANY (US) 1982-02-09 US disclosed