SCHEMBL9759560

SCHEMBL9759560

[CH2]C(N)CNC(=O)C(=C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.38
TDP1 Q9NUW8 1/20 0.35
RXFP1 Q9HBX9 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL54007 0.83 TGFBR1 (0.38) TGFBR1TDP1RXFP1ALDH1A1
Hydrochloric Acid SCHEMBL452931 0.81 TGFBR1 (0.37) TGFBR1TDP1RXFP1ALDH1A1
SCHEMBL9759569 0.80 TGFBR1 (0.39) TGFBR1TDP1RXFP1ALDH1A1
SCHEMBL9289423 0.80 TGFBR1 (0.39) TGFBR1TDP1RXFP1ALDH1A1
SCHEMBL10187391 0.79 GFPT1 (0.46) TGFBR1
SCHEMBL10671185 0.78 TGFBR1 (0.38) TGFBR1RXFP1ALDH1A1
SCHEMBL28061019 0.78 TGFBR1 (0.35) TGFBR1TDP1ALDH1A1
SCHEMBL366427 0.77 CYP2D6 (0.52) TGFBR1TDP1RXFP1ALDH1A1
SCHEMBL97375 0.77 TGFBR1 (0.41) TGFBR1TDP1RXFP1ALDH1A1
SCHEMBL3738357 0.77 TGFBR1 (0.41) TGFBR1TDP1RXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5055377-A LIGHT-SENSITIVE RECORDING ELEMENT AND PROCESS OF FORMING A RELIEF IMAGE WHEREIN THE RECORDING ELEMENT CONTAINS LECITHIN AS AN ADDITIVE BASF AKTIENGESELLSCHAFT (DE) 1991-10-08 US disclosed
US-5035981-A Having a top layer of high-strength, transparent, soluble or swellable polymer containing an antistatic agent of an ethoxylated amine or amide; exposure; development BASF AKTIENGESELLSCHAFT (DE) 1991-07-30 US disclosed
US-4946758-A RELIEF IMAGE FORMING LAYER; HIGH TENSILE STRENGTH POLYMER AND COVERING BASF AKTIENGESELLSCHAFT (DE) 1990-08-07 US disclosed
US-4900795-A PHOTOPOLMERIZABLE POLYMER COMPRISING ETHYLENE, (METH)ACRYLIC ACID AND VINYL OR ACRYLATE MONOMER NEUTRALIZED BY A CYCLIC AMINE OR HYDROXY-CONTAINING AMINE; PHOTORESISTS; PRINTING PLATES; OZONE RESISTANCE; ELONGATION; TENSILE STRENGTH BASF AKTIENGESELLSCHAFT (DE) 1990-02-13 US disclosed
US-4762892-A ETHYLENE-ACRYLIC OR METHACRYLIC ACID-ALKYL ACRYLATE MODIFIED TO CONTAIN UNSATURATED SIDE CHAINS BASF AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed