SCHEMBL9759775

SCHEMBL9759775

CC(=O)c1ccc2cc3ccccc3cc2c1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.55
ALDH1A1 P00352 4/20 0.55
HPGD P15428 3/20 0.55
CYP1A2 P05177 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
GLA P06280 1/20 0.55
CYP2C19 P33261 1/20 0.55
HSD17B10 Q99714 1/20 0.55
GAA P10253 1/20 0.45
MAPT P10636 2/20 0.44
WDR5 P61964 1/20 0.43
CDC25B P30305 3/20 0.42
LDHA P00338 1/20 0.42
MAOB P27338 3/20 0.40
SOS1 Q07889 1/20 0.40
IDO1 P14902 1/20 0.40
CA12 O43570 1/20 0.38
NT5E P21589 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666909 0.90 ALDH1A1 (0.47) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL1667139 0.88 KDM4E (0.46) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL1669176 0.88 KDM4E (0.46) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL43510 0.88 KDM4E (0.60) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL29506855 0.88 KDM4E (0.60) KDM4EALDH1A1HPGDCYP1A2MEN1
Potassium SCHEMBL31214909 0.86 KDM4E (0.58) KDM4EALDH1A1HPGDCYP1A2MEN1
Rubidium SCHEMBL31214825 0.86 KDM4E (0.58) KDM4EALDH1A1HPGDCYP1A2MEN1
Cesium SCHEMBL31214904 0.86 KDM4E (0.58) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL31676317 0.86 KDM4E (0.58) KDM4EALDH1A1HPGDCYP1A2MEN1
Lithium SCHEMBL31214857 0.86 KDM4E (0.58) KDM4EALDH1A1HPGDCYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3086811-A None JP disclosed
JP-H0386811-A COSMETIC COMPOSITION UNILEVER NV 1991-04-11 JP disclosed