Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9760154 | 0.99 | ADRA2A (0.56) | ADRA2AADRA2BDRD2DRD3ADRA1B | |
| Tioperidone SCHEMBL29385311 | 0.99 | ADRA2A (0.58) | ADRA2AADRA2BDRD2DRD3ADRA1B | |
| Tioperidone SCHEMBL122658 | 0.98 | ADRA2A (0.57) | ADRA2AADRA2BDRD2DRD3ADRA1B | |
| Hydrochloric Acid SCHEMBL9760181 | 0.94 | ADRA2A (0.56) | ADRA2AADRA2BDRD2DRD3ADRA1B | |
| Hydrochloric Acid SCHEMBL9760160 | 0.90 | ADRA2A (0.59) | ADRA2AADRA2BDRD2DRD3ADRA1B | |
| Hydrochloric Acid SCHEMBL9760407 | 0.88 | LMNA (0.49) | ADRA2AADRA2BDRD2DRD3ADRA1B | |
| Hydrochloric Acid SCHEMBL9760163 | 0.88 | USP2 (0.52) | ADRA2AADRA2BDRD2DRD3ADRA1B | |
| Hydrochloric Acid SCHEMBL9759793 | 0.88 | TP53 (0.48) | ADRA2AADRA2BDRD2DRD3ADRA1B | |
| SCHEMBL9447015 | 0.84 | ADRA2A (0.59) | ADRA2AADRA2BDRD2DRD3ADRA1B | |
| Hydrochloric Acid SCHEMBL9759559 | 0.84 | ADRA2A (0.58) | ADRA2AADRA2BDRD2DRD3ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991012006-A2 | TUMOR CELL SENSITIZATION METHOD | WARNER-LAMBERT COMPANY (US) | 1991-08-22 | — | — | WO | disclosed |