Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877285 | 0.83 | CYP3A4 (0.59) | CYP3A4ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL7884025 | 0.81 | ALDH1A1 (0.47) | CYP3A4ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL20752715 | 0.79 | ALDH1A1 (0.39) | CYP3A4ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL3838045 | 0.78 | TSHR (0.64) | CYP3A4ALDH1A1TSHRTDP1KDM4E | |
| Ammonia Solution, Strong SCHEMBL197887 | 0.77 | TSHR (0.61) | CYP3A4ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL13995819 | 0.76 | TSHR (0.55) | CYP3A4ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL13995800 | 0.76 | TSHR (0.55) | CYP3A4ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL15203130 | 0.76 | TSHR (0.55) | CYP3A4ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL11346834 | 0.76 | CYP3A4 (0.67) | CYP3A4ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL172603 | 0.75 | ALDH1A1 (0.59) | CYP3A4ALDH1A1TSHRTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049680-A | Cationic polymers | LCE PARTNERSHIP (US) | 1991-09-17 | — | — | US | disclosed |