Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197886 | 0.84 | CYP3A4 (0.53) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL16390075 | 0.81 | TSHR (0.59) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL3838045 | 0.80 | TSHR (0.64) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL15418382 | 0.79 | ALDH1A1 (0.52) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL3877285 | 0.77 | CYP3A4 (0.59) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL4162585 | 0.77 | TSHR (0.59) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL172603 | 0.77 | ALDH1A1 (0.59) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL9759802 | 0.77 | CYP3A4 (0.59) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL23611735 | 0.77 | TSHR (1.00) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL14365914 | 0.77 | TSHR (1.00) | TSHRALDH1A1CYP3A4TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642253-B1 | BLOCKING AGENTS FOR AMINES, LATENT CURING AGENTS AND POLYURETHANE COMPOSITIONS | SIKA TECH AG (CH) | 2023-05-10 | — | — | EP | disclosed |
| US-11518736-B2 | Blocking agent for amines, latent hardeners and polyurethane compositions | SIKA TECHNOLOGY AG (CH) | 2022-12-06 | — | — | US | disclosed |
| EP-3394132-B1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECH AG (CH) | 2022-11-09 | — | — | EP | disclosed |
| EP-3394139-B1 | POLYURETHANE COMPOSITION WITH LOW PLASTICIZER MIGRATION | SIKA TECH AG (CH) | 2022-07-20 | — | — | EP | disclosed |
| US-20220144746-A1 | PROCESS FOR PRODUCING 2,2-DIALKYL-3-ACYLOXYPROPANALS | SIKA TECHNOLOGY AG (CH) | 2022-05-12 | — | — | US | disclosed |
| US-11214706-B2 | Polyurethane composition with low plasticiser migration | SIKA TECHNOLOGY AG (CH) | 2022-01-04 | — | — | US | disclosed |
| US-11161930-B2 | Two component polyurethane composition | SIKA TECHNOLOGY AG (CH) | 2021-11-02 | — | — | US | disclosed |
| US-20210246101-A1 | BLOCKING AGENT FOR AMINES, LATENT HARDENERS AND POLYURETHANE COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2021-08-12 | — | — | US | disclosed |
| US-10442956-B2 | Solvent-free polyurethane liquid membrane | SIKA TECHNOLOGY AG (CH) | 2019-10-15 | — | — | US | disclosed |
| US-20180371148-A1 | TWO COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2018-12-27 | — | — | US | disclosed |
| US-20100130674-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2010-05-27 | — | — | US | disclosed |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-04-29 | — | — | US | disclosed |
| US-20100006221-A1 | Amorphous polyurethane polymer and its use in hotmelt adhesives | SIKA TECHNOLOGY AG (CH) | 2010-01-14 | — | — | US | disclosed |
| US-20100003526-A1 | Polyurethane composition with good initial strength | SIKA TECHNOLOGY AG (CH) | 2010-01-07 | — | — | US | disclosed |
| US-7629433-B2 | Odor-less during hydrolytic deblocking, separation; for use as source for aldehydes; crosslinking agents | SIKA TECHNOLOGY AG (CH) | 2009-12-08 | — | — | US | disclosed |
| US-20090176944-A1 | Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof | SIKA TECHNOLOGY AG (CH) | 2009-07-09 | — | — | US | disclosed |
| US-20090159204-A1 | Moisture-Hardened Polyurethane Compositions Containing Compounds Comprising Aldimine | SIKA TECHNOLOGY AG | 2009-06-25 | — | — | US | disclosed |
| US-20090099333-A1 | Compounds Containing Aldimine | SIKA TECHNOLOGY AG (CH) | 2009-04-16 | — | — | US | disclosed |
| US-20080280145-A1 | moisture-reactive hot-melt adhesive which comprises at least one aldimine and at least one polyurethane polymer ( polyesterurethane copolymer, polyetherurethane copolymer)which contains isocyanate groups and is solid at room temperature; bonded assembly is notable for improved adhesive | SIKA TECHNOLOGY AG (CH) | 2008-11-13 | — | — | US | disclosed |
| US-20080251204-A1 | Reactive Polyurethane-Hot Melt Adhesive Having a Low Isocyanate-Monomer Content | SIKA TECHNOLOGY AG (CH) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518736-B2 | Blocking agent for amines, latent hardeners and polyurethane compositions | ODC1, KDM2B, ALKBH2 | TSHR 4857/4885ALDH1A1 20/4885CYP3A4 3753/4885 |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDH7A1, ILK, ALDH3A1 | TSHR 4884/4885ALDH1A1 5/4885CYP3A4 2317/4885 |
| US-20090176944-A1 | Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof | ADH5, ADH1C, ADH1A | TSHR 4062/4885ALDH1A1 5/4885CYP3A4 329/4885 |
| US-20210246101-A1 | BLOCKING AGENT FOR AMINES, LATENT HARDENERS AND POLYURETHANE COMPOSITIONS | ODC1, KDM2B, ALKBH2 | TSHR 4857/4885ALDH1A1 20/4885CYP3A4 3753/4885 |
| US-20220144746-A1 | PROCESS FOR PRODUCING 2,2-DIALKYL-3-ACYLOXYPROPANALS | ADCY4, ADCY1, ADCY2 | TSHR 3940/4885ALDH1A1 19/4885CYP3A4 2232/4885 |
| US-20090099333-A1 | Compounds Containing Aldimine | ALDH7A1, ALDH3A1, ALDH1A1 | TSHR 4769/4885ALDH1A1 3/4885CYP3A4 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.